Real-Time PCR Kit
SMA
A motor neuron disorder that affects the anterior horn cells in the spinal cord and results in muscle weakening and shrinking is known as spinal muscular atrophy (SMA). The illness, which is quite uncommon in society, worsens with time, causing an increasing loss of nerve cells and muscle mass. Preventive medications help patients live better, longer lives by slowing the advancement of their disease and improving their quality of life. Researchers are working to develop novel therapies for SMA throughout the world.
For families dealing with the frustrating process of diagnosing SMA, Anatolia Geneworks has created a gene-based Real-Time PCR kit that reveals SMA risk in a premarital setting. Thus, people can safely plan their families before their babies are born by learning their carrier status and taking the necessary precautions.
Features
Workflow
Technical Specifications
| Sample Typing |
Whole blood, dry blood spots
|
| Shelf Life | 18 Months |
| Channels | FAM, HEX |
| Shipping / Storage | -80°C / -20°C |
SMA Detection Kit
The Bosphore SMA Detection Kit v1 is intended to identify the presence and copy number of the SMN1 allele for SMA risk assessments in whole blood samples from those who wish to become parents. The delta-delta Ct technique is used to compute the analysis.
Internal control was introduced to the kit for control purposes in situations such as the lack of the SMN1 allele in the samples, and isolation or experimental mistakes. The delta-delta Ct analysis is based on this internal control. Additionally, three distinct control DNAs are included in the Bosphore SMA Detection Kit v1. They are normal, deletion, and carrier genotypes. Each experiment must include these controls in order to compare results effectively.
