Meningitis Panel

Bosphore Bacterial Meningitis Panel Kit v2 detects and characterizes Haemophilus influenzae, Neisseria meningitidis, Streptococcus pneumoniae, Escherichia coli K1, and Cryptococcus gattii/Cryptococcus neoformans in human biological samples including serum, plasma, tissue/biopsy samples and CSF (gold standard).

An internal control has been integrated into the kit in order to check DNA extraction, PCR inhibition and application mistakes. The internal control can be added either during DNA extraction or PCR step.

Bosphore Bacterial Meningitis Panel Kit v3 is a Real-Time PCR kit for in vitro diagnostics that detects and characterizes the omp6 gene of Haemophilus influenzae, ctrA gene of Neisseria meningitidis and lytA gene of Streptococcus pneumoniae from whole blood, serum, plasma, tissue/biopsy samples, and CSF* samples. Fluorescence detection is performed using FAM, HEX, Texas RED, and Cy5 filters. Haemophilus influenzae DNA is amplified and fluorescence detection is performed using the FAM filter, Neisseria meningitidis DNA is amplified and fluorescence detection is performed using the HEX filter, and Streptococcus pneumoniae DNA is amplified and fluorescence detection is performed using the Texas RED filter.

* CSF samples are the “gold standard” for the diagnosis of meningitis.

Internal control has been integrated into the kit to check DNA extraction, PCR inhibition, or application problems. The amplification data of the internal control is detected with the Cy5 filter. The internal control can be added either during DNA extraction or the PCR step.

Bosphore Neonatal meningitis Panel Kit v1 is a Real-Time PCR kit for in vitro diagnostics that detects and characterizes the uidA gene of Escherichia coli, cAMP gene of Streptococcus agalactiae (Group B), and hly gene of Listeria monocytogenes from serum, plasma, and CSF samples. Fluorescence detection is performed using FAM, HEX, Texas RED, and Cy5 filters. Escherichia coli DNA is amplified and fluorescence detection is performed using the FAM filter, Streptococcus agalactiae (Group B) DNA is amplified and fluorescence detection is performed using the HEX filter and Listeria monocytogenes DNA is amplified and fluorescence detection is performed using the Cy5 filter.

Internal control has been integrated into the kit to check DNA extraction, PCR inhibition, or application problems. The amplification data of the internal control is detected with the Texas RED filter. The internal control can be added either during DNA extraction or the PCR step.

Bosphore Neonatal Meningitis Panel Kit v2 detects and characterizes Escherichia coli, Streptococcus agalactiae (Group B), Listeria monocytogenes and Streptococcus pneumoniae in human biological samples. Fluorescence detection is accomplished using the FAM, HEX, Texas Red and Cy5 filters. In the first PCR tube with PCR Master Mix 1, Escherichia coli DNA is amplified and fluorescence detection is accomplished using the FAM filter, Streptococcus agalactiae (Group B) DNA is amplified and fluorescence detection is accomplished using the HEX filter and Listeria monocytogenes DNA is amplified and fluorescence detection is accomplished using the Cy5 filter. In the second PCR tube with PCR Master Mix 2, Streptococcus pneumoniae DNA is amplified and fluorescence detection is accomplished using the HEX filter.

An internal control has been integrated into the kit in order to check DNA extraction, PCR inhibition or application problems. The internal control can be added either during DNA extraction or PCR step.

Bosphore Viral Meningitis Panel Kit v2 detects and characterizes herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, enterovirus (Coxsackie A and B, echovirus, poliovirus and enterovirus 68-71), parechovirus and mumps DNA and RNA in human biological samples including serum, plasma, tissue/biopsy samples and CSF (gold standard) in two PCR tubes. Fluorescence detection is accomplished by using FAM, HEX, Texas Red and Cy5 filters.

An internal control has been integrated into the kit in order to check DNA extraction, PCR inhibition and application errors in the samples. The internal control can be added either during DNA/RNA extraction or PCR step.

Bosphore Viral Meningitis Panel Kit v3 detects and characterizes herpes simplex virus 1, herpes simplex virus 2, varicella-zoster virus, enterovirus (coxsackie A and B, echovirus, poliovirus and enterovirus 68 – 71) and parechovirus DNA and RNA in human biological samples including serum, plasma, tissue/biopsy samples and CSF (gold standard) in two PCR tubes. Fluorescence detection is accomplished by using FAM, HEX, Texas RED and Cy5 filters.

An internal control has been integrated into the kit in order to check DNA extraction, PCR inhibition and application errors in the samples. Internal control can be added either during DNA/RNA extraction or PCR step.