Bosphore® FMF Mutation Analysis Kit v3, is a Real-Time PCR-based in vitro diagnostic medical device, IVD CE marked according to 98/79/EC Directive. Bosphore® FMF Mutation Analysis Kit v3 detects the mutations M694I, M694V, M680I/GA, M680I/GC,V726A, R761H,A744S, K695R,I692del, K695M, M694L on Exon 10, P369S on Exon 3, F479L on Exon 5 and E148Q, R202Q mutations on Exon 2 of MEFV gene in human blood samples. Wild type alleles are amplified and fluorescence detection is accomplished using the HEX filter. Mutant alleles are amplified and fluorescence detection is accomplished using the FAM filter.
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