Bosphore FMF Mutation Analysis Kit v1

Bosphore® FMF Mutation Analysis Kit v1, is a Real-Time PCR-based in vitro diagnostic medical device, IVD CE marked according to 98/79/EC Directive. Bosphore® FMF Mutation Analysis Kit v1 detects the mutations M694I, M694V, M680I-GA, M680I-GC, V726A, R761H on Exon 10 and E148Q mutation on Exon 2 of MEFV gene in human blood samples. Wild type alleles are amplified and fluorescence detection is accomplished using the HEX filter. Mutant alleles are amplified and fluorescence detection is accomplished using the FAM filter.

 

  • In the 1st well: M694I mutation,
  • 2nd well: M694V mutation,
  • 3rd well: Guanine-Adenine alteration resulted M680I mutation,
  • 4th well: Guanine-Cytosine alteration resulted M680I mutation,
  • 5th well: V726A mutation,
  • 6th well: R761H mutation
  • 7th well: E148Q mutations are detected. 

 

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REAL-TIME PCR DEVICES