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Hepatitis Kits

The hepatitis C virus is a hepacivirus of the Flaviviridae family of viruses that causes Hepatitis C in humans. It is a small, enveloped, single-stranded RNA virus divided among six main genotypes with more than one hundred different subtypes. [1] It is estimated that HCV has a worldwide prevalence of 3% affecting around 180 million people with between 3 to 4 million new infections each year. The vast majority of infected people (70-90%) develop chronic infection. Though chronic infection may be asymptomatic, it is a leading cause of chronic liver diseases, including cirrhosis in between 20 to 50% of patients. Treatments may be effective in 10-50% of patients depending on the applied therapy. [2]

Bosphore HCV Detection Kit v1

Bosphore HCV Genotype 3 Genotyping Kit v1

Bosphore HCV Genotyping Kit v1 (1a/1b/1c-k/2/3/4)

Bosphore HCV Genotyping Kit v3 (1a/1b/1c-k/2/3/4/ 5/6)

Bosphore HCV Quantification Kit

Bosphore Ultra HCV Quantification / Detection Kit

Bosphore HBV-HCV Multiplex Screening Kit v1

Bosphore HBV-HCV-HIV Multiplex Screening Kit

 

 

Hepatitis delta virus (HDV) has an epidemiological distribution similar to HBV. It has been found worldwide with unequal distribution rates. There are around 10 million people infected with HDV around the world. It has mostly similar distribution patterns of HBV infection, but with different rates. There is a highest incidence HDV infection in Southern Italy, the Mediterranean region and in some parts of Africa and Asia. There is an average incidence of HDV infection in Turkey. 10% of the patients with HBV in the west and 15-25% of patients in the central and eastern regions have positive for anti-HDV. [3], [4]

Bosphore HDV Quantification-Detection Kit v1

 

Hepatitis B virus (HBV) is one of the smallest enveloped double-stranded DNA virus that is part of the Hepadnaviridae family.  The replication process of HBV that takes place in liver is unique among animal DNA viruses where herein, reverse transcription is involved. It destroys the liver and causes diseases such as cirrhosis and hepatocellular carcinoma. There are 8 distinctly classified genotypes of hepatitis B virus and further recognized subgenotypes. [1], [5]

Bosphore HBV Detection Kit v1

Bosphore HBV Genotype D Genotyping Kit v1

Bosphore HBV Quantification Kit

Bosphore Ultra HBV Quantification / Detection Kit

 

REFERENCES

1- K. E. Nelson, C. Williams, and N. Graham., Infectious Disease Epidemiology: Theory and Practice, July 15, 2000
2- 
Theodore Sy and M. Mazen Jamal, Epidemiology of Hepatitis C Virus (HCV) Infection, Int J Med Sci. 2006; 3(2), p:41–46.

3- Mario Rizzetto, Hepatitis D: the comeback?, Liver International 2009; 29(s1): 140–142 

4- Değertekin H., Yükselen A. V., Dursun M., Yalçın K., Seroepidemiology of delta hepatitis in Turkey, 1999;10: 316-327.
5- Barbara Rehermann and Michelina Nascimbeni, Immunology of Hepatitis B virus and Hepatitis C virus Infection, NATURE REVIEWS , Volume 5, March 2005, p: 215-229